Antibiotics in Septic Shock: Is Time Really of the Essence?

01 Sep

Posted by SCCM as Concise Critical Appraisal

The Surviving Sepsis Campaign guidelines recommend initiating broad-spectrum antibiotics within one hour to treat severe sepsis or septic shock. In September’s Critical Care Medicine, Puskarich et al studied the association between time to initial antibiotic administration and in-hospital mortality rates for septic patients treated with the quantitative resuscitation protocol. The study design was a preplanned [...]

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Positive Outcomes Following Tele-ICU Implementation

16 Jun

Posted by SCCM as Concise Critical Appraisal

In the June 1, 2011 Journal of American Medical Association, Lilly and colleagues report a prospective, unblinded single-institution study where implementation of a tele-ICU intervention was associated with reduced adjusted odds of mortality and reduced hospital and intensive care unit (ICU) length of stay, as well as improved adherence to best practices and lower rates [...]