Increased Risk of Death with Insulin Control and Hypoglycemia

28 Sep

Posted by SCCM as Concise Critical Appraisal

The Normoglycemia in Intensive Care Evaluation-Survival Using Glucose Algorithm Regulation (NICE-SUGAR) trial recruited 6,104 intensive care unit (ICU) patients in 24 hospitals. In this post hoc analysis of the trial’s database, the NICE-SUGAR investigators explored the association between different levels of hypoglycemia and death. Findings were published in the September 20 issue of The New [...]

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Is Too Much Fluid Bad for Patients With SAH?

19 Sep

Posted by SCCM as Concise Critical Appraisal

Induced hypertension, hypervolemia and hemodilution (triple-H) therapy has historically been considered to be beneficial for the treatment of vasospasm in patients with non-traumatic subarachnoid hemorrhage (SAH). In the October issue of Neurocritical Care, Martini and colleagues from the Oregon Health and Science University and University of Washington sought to determine the association between early fluid [...]

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Corticosteroids and Outcomes for Patients with Pneumonia

05 Sep

Posted by SCCM as Concise Critical Appraisal

Intensive care unit (ICU) patients are often prescribed systemic corticosteroids for a wide variety of indications, including chronic obstructive lung disease and multiple trauma injuries. To assess the characteristics and outcomes of patients with ICU-acquired pneumonia that received steroids, Ranzani and colleagues performed a prospective observational study at a major university teaching hospital in Barcelona, [...]