Results of the EDEN Trial: Full vs. Trophic Enteral Feeding

28 Feb

Posted by SCCM as Concise Critical Appraisal

The amount of artificial nutrition required to optimize outcomes in patients with acute lung injury (ALI) is unknown. To address this problem, the Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network, headed by Todd Rice, MD, MS, from VanderbiltUniversityinNashville,Tennessee,USA, conducted a prospective, randomized open-label trial comparing the effect of initial trophic enteral feeding vs. initial [...]

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Prone vs. Supine Positioning and ARDS: Long-Term Outcomes?

01 Feb

Posted by SCCM as Concise Critical Appraisal

Despite advances in mechanical ventilation and critical care, the mortality rate for acute respiratory distress syndrome (ARDS) remains over 40%. In addition to mortality, health-related quality of life (HRQL) is also thought to be impacted negatively. Prone positioning has been used in ARDS to attenuate lung injury and to provide a more homogeneous distribution of [...]